Dr Zulya Maizetova
Dr Maizetova received her medical degree and her Masters in Dermatology at the Medical University of St Petersburg .Dr Maiztova has an integrated method of prevention and reversal of skin aging through specific treatments to improve the body’s own ability to regenerate itself. This method is safe , non-toxic and non –invasive. Dr Zulya Maizetova uses her successful integrated medical approach to treat and prevent skin diseases and aging, allergies, weight problems, environmental and heavy metal toxicity ,hair loss and many other ailments.

Resveratrol - A real benefit or just a conundrum
Genetic polymorphisms and their correlation with phenotype heterogeneity in 100 subjects with chronic cerebrovascular disease in the Grand Duchy of Luxembourg.
Laboratoires Réunis, Junglinster, Luxembourg; 2 Centre Hospitalier de Luxembourg, Luxembourg

Cerebro-cardio-vascular diseases are estimated to be the leading cause of death and loss of disability-adjusted life years. In the present study, 25 patients received intensive lifestyle advice, 25 received intensive lifestyle advice plus the advice to drink a glass of red wine each day, 25 received the advice to drink only a glass of red wine each day, and the remaining 25 followed their usual lifestyle.

The genetic analysis was carried out to explore the importance of a number of single nucleotide polymorphisms (SNP) located in several genes, which are related to energy expenditure, adipogenesis, insulin resistance, blood pressure regulation and body composition. The analysed SNPs were: KIF6 (rs20455), PON1 (Q192R), APOA1 (G-75A), PPARgamma (P12A), FABP2 (A54T), SELP (V640L), SELE (S149R), C5 (rs17611), ADH1C (G78X), ICAM (rs309303), C3 (rs11569562), ApoE (E2/E3/E4), TNFalpha (G-238A), CETP (G-279A), CETP (I405V) and CRP (T-717C).   

We found a correlation between different patterns of SNPs and the response to diet. We could also detect SNP-dependent differences in mean systolic blood pressure in the two diet/sports arms and a difference of the LDL/HDL ratio in the two wine arms compared to the control group.

Further analysis will give a better understanding of gene-environment interactions in metabolic pathways associated with pathological symptoms related to diet and to lack of physical activities as well as with the risk of cardiovasculer diseases, especially of cerebrovascular diseases. The purpose is to develop better target therapeutics upon individual physiological response to dietary and lifestyle habits that vary in the population and are related to different genetic backgrounds.

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