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Prof Stefan Krauss PhD
Section for cellular and genetic therapy - Institute of Medical Microbiology, Rikshospitalet University Hospital NO-0027, Oslo, Norway
Prof. Stefan Krauss is group leader in
the Section for Cellular and Genetic Therapy, Institute of Medical
Microbiology at the Rikshospitalet University Hospital in Oslo. He
discovered the central morphogen Sonic hedgehog (Shh) (Cell 1993,
75:1431) and has since then created several transgenic models for
studying forebrain stem cell biology (e.g. Hesx1, Dach1, D6-b-cat
conditional KO, D6 DA-b-cat). The long term goal of the laboratory
of Stefan Krauss is to improve the understanding of the events that
occur upon therapeutic stem cell transplantation from the point of
cellular signaling.
2006 - Forbrain development and neural stem cells
The
development biology laboratory investigates the signalling mechanisms
that control fate specification and proliferation in the mouse cortex.
The
aim of the ongoing study is to deepen our understanding of signalling
pathways that are involved in cortical development, sub-specification
of cortical areas, proliferation and communication between supporting
cells Disease models will be established that shall cast light on the
function of morphogenetic signals in ageing and dementia.This knowledge
should help to develop new strategies for prevention and treatment
of disease, either by identifying drug targets, or by developing cell
based delivery of therapeutic signals.
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